Rifamycin S (CAS 13553-79-2) is supplied by Monuo Chemical for specialty chemical and custom synthesis purchasing. Buyers typically search by rifamycin S, rifamycin quinone or CAS when sourcing a defined ansamycin antibiotic intermediate for pharmaceutical R&D, impurity reference and analytical method work.
Key Specifications at a Glance
| Product Name | Rifamycin S |
|---|---|
| CAS Number | 13553-79-2 |
| Molecular Formula | C37H45NO12 |
| Molecular Weight | 695.75 g/mol |
| Chemical Class | Ansamycin antibiotic / rifamycin-series quinone intermediate |
| Purity / Specification | 98% (confirm assay on the batch COA) |
| Typical Use Area | Pharmaceutical intermediate supply; API impurity / pharmacopeial reference; antibacterial R&D |
| Category | Custom synthesis |
| Documents | COA, TDS, SDS on request |
| Supply Origin | China | Worldwide shipping |
What Is Rifamycin S?
Rifamycin S (CAS 13553-79-2) is a quinone-form ansamycin antibiotic in the rifamycin family, chemically described as rifamycin 1,4-dideoxy-1,4-dihydro-1,4-dioxo- in supplier nomenclature. Molecular formula C37H45NO12; molecular weight about 695.75 g/mol. Rifamycin S is obtained from rifamycin B via oxidation and hydrolysis routes and serves as a key precursor in the preparation of clinically used rifamycin derivatives such as rifampicin (rifampin), rifabutin, rifapentine and rifaximin. Always match CAS 13553-79-2 on the batch COA.
Pharmacology literature describes rifamycins as bactericidal agents that inhibit bacterial DNA-dependent RNA polymerase. Reference-standard catalogs also list rifamycin S as a pharmacopeial / impurity reference (for example rifaximin EP impurity E and rifamycin EP impurity B nomenclature). Monuo Chemical supplies rifamycin S as a specialty chemical raw material under Custom synthesis, with batch identity documentation (COA / SDS). It is supplied for research and process-development purchasing—not as a finished pharmaceutical product. Finished-product claims, labeling and local regulatory filings remain the customer’s responsibility. Confirm assay and structure against the batch COA for your intended method.
Synonyms & Search Names
- Rifamycin S
- Rifamycin, 1,4-dideoxy-1,4-dihydro-1,4-dioxo-
- Rifaximin EP Impurity E / Rifaximin impurity 5
- Rifamycin EP Impurity B (catalog nomenclature)
- Rifamycin S CRS (reference standard nomenclature)
- CAS 13553-79-2
Applications
In specialty chemical and custom synthesis projects, rifamycin S is commonly reviewed for:
- Pharmaceutical intermediate supply in routes toward rifampicin and related rifamycin APIs
- API impurity identification, forced-degradation and pharmacopeial reference work
- HPLC / LC-MS analytical method development for rifamycin-series materials
- Antibacterial mechanism-of-action and RNA polymerase research in laboratory settings
- Catalog purchasing for defined CAS-matched ansamycin reference compounds
Compare related specialty items such as 25-Desacetylrifapentine (CAS 79039-56-8) and Novobiocin sodium (CAS 1476-53-5) in the same Custom synthesis range.
Handling & Use Notes
- Assay check: Confirm purity / HPLC assay for rifamycin S on the batch COA before use.
- Light and moisture: Rifamycin derivatives are often light-sensitive; keep sealed and protect from unnecessary light and moisture.
- Redox awareness: Rifamycin S participates in reversible oxidation–reduction chemistry with rifamycin SV; handle and store per your analytical SOP.
- Safety: Follow the SDS for storage, PPE and waste handling. Use the batch SDS as the controlling safety document.
Need assay or packing discussion? Email [email protected] or use the contact form.
Packaging, Storage & Logistics
| Standard Pack Sizes | 50 g / 100 g bottles; 500 g / 1 kg packs (custom packing available) |
|---|---|
| Storage | Keep sealed, dry and protected from light and heat. Follow the batch COA and SDS |
| Shelf Life | Confirm shelf life on the COA for each lot |
| MOQ | Commercial MOQ discussed per project (often from 50 g); larger packs available on request |
| Lead Time | Stock items often ship promptly; custom pack / large lots typically 7–14 working days |
Quality & Documentation
For rifamycin S (CAS 13553-79-2), Monuo Chemical can provide:
- Certificate of Analysis (COA)
- Technical Data Sheet (TDS) and Safety Data Sheet (SDS)
- CAS / product-name confirmation for your purchase file
- Flexible packing from grams to kilograms
- FOB / CIF / DAP terms as agreed
Our team aims to return technical data and quotations within 24 hours. See also Custom synthesis.
Request a Quote
Share your target assay, pack size and destination. We will confirm availability and documentation for rifamycin S CAS 13553-79-2.
Request a Quote | Email: [email protected]
Frequently Asked Questions
What is rifamycin S (CAS 13553-79-2)?
It is a quinone-form ansamycin antibiotic and key rifamycin-series intermediate used in pharmaceutical R&D. Monuo Chemical lists it under Custom synthesis. Match CAS 13553-79-2 on the batch COA.
How is rifamycin S related to rifampicin?
Supplier and pharmacology references describe rifamycin S as a precursor intermediate in semisynthetic routes toward rifampicin and other clinically used rifamycin derivatives.
Where is rifamycin S typically used?
Applications cited in catalogs include pharmaceutical intermediate supply, impurity / pharmacopeial reference work and antibacterial mechanism research. Finished-product claims remain the customer’s responsibility.
What is the molecular formula and weight?
Molecular formula C37H45NO12; molecular weight about 695.75 g/mol. Confirm on the batch COA/TDS.
What specification does Monuo Chemical supply?
Catalog listing notes 98%; exact assay and impurity profile are confirmed on the Certificate of Analysis for each lot. Share your target specification when you request a quote.
Is rifamycin S a plant extract?
No. It is a fermentation-derived ansamycin antibiotic intermediate, correctly categorized under Custom synthesis.
How should rifamycin S be stored?
Keep sealed, dry and protected from light and heat. Follow the batch SDS and COA for controlling storage conditions.
Which related Custom synthesis products can I review?
You may also review 1-N-Ethylgaramine sulfate (CAS 864371-49-3) and 1,3-Diacetyl-2-imidazolidinone (CAS 5391-40-2), or open the full Custom synthesis catalog.
Related Products
- 25-Desacetylrifapentine (CAS 79039-56-8)
- Novobiocin sodium (CAS 1476-53-5)
- 1,3-Diacetyl-2-imidazolidinone (CAS 5391-40-2)
- View all Custom synthesis
Disclaimer: Information is for specialty chemical raw-material identification and technical reference. This material is supplied for research / process-development use as described on the COA—not as a finished pharmaceutical or consumer product. Finished-product claims and regulatory filings remain the customer’s responsibility. Verify each lot against the supplied COA and SDS. Trade terms are FOB / CIF / DAP as agreed.
