Tributylamine (dichloromethylene)bis(phosphonate) (CAS 163706-61-4) is supplied by Monuo Chemical for specialty chemical and custom synthesis purchasing. It is also referenced as phosphonic acid, P,P’-(dichloromethylene)bis-, compd. with N,N-dibutyl-1-butanamine (1:1) and Cangrelor intermediate. Buyers typically search by product name or CAS when sourcing bisphosphonate intermediates for pharmaceutical synthesis projects.
Key Specifications at a Glance
| Product Name | Tributylamine (dichloromethylene)bis(phosphonate) |
|---|---|
| CAS Number | 163706-61-4 |
| Molecular Formula | C13H31Cl2NO6P2 |
| Molecular Weight | 430.24 g/mol |
| Chemical Class | Tributylammonium bisphosphonate salt / pharmaceutical intermediate |
| Appearance | White to off-white powder (supplier literature) |
| Purity / Specification | 98%; confirm assay on the batch COA |
| Typical Use Area | Pharmaceutical intermediate R&D; Cangrelor synthesis supply |
| Category | Custom synthesis |
| Documents | COA, TDS, SDS on request |
| Supply Origin | China | Worldwide shipping |
What Is Tributylamine (dichloromethylene)bis(phosphonate)?
Tributylamine (dichloromethylene)bis(phosphonate) (CAS 163706-61-4) is the 1:1 salt of dichloromethylene bisphosphonic acid (clodronic acid) with tributylamine. Molecular formula C13H31Cl2NO6P2; molecular weight about 430.24 g/mol. Always match CAS 163706-61-4 on the batch COA.
Catalog literature describes this material as a Cangrelor API intermediate used to introduce the metabolically stable dichloromethylene bisphosphonate moiety into nucleotide-analog synthesis routes. The tributylammonium counterion improves organic-solvent solubility and supports phosphorylation / condensation steps in validated process workflows. Monuo Chemical supplies this compound as a specialty chemical raw material under Custom synthesis, with batch identity documentation (COA / SDS). Finished-product claims, labeling and local regulatory filings remain the brand manufacturer’s responsibility. Confirm grade and assay against the batch COA for your intended method.
Synonyms & Search Names
- Tributylamine (dichloromethylene)bis(phosphonate)
- Phosphonic acid, P,P’-(dichloromethylene)bis-, compd. with N,N-dibutyl-1-butanamine (1:1)
- Cangrelor intermediate / Cangrelor API intermediate
- P2Y12 inhibitor Cangrelor intermediate
- Clodronic acid tributylamine salt (catalog description)
- CAS 163706-61-4
Applications
In specialty pharmaceutical intermediate and custom synthesis projects, Tributylamine (dichloromethylene)bis(phosphonate) is commonly reviewed for:
- Cangrelor synthesis routes requiring a defined dichloromethylene bisphosphonate building block
- Nucleotide-analog phosphorylation / condensation steps where a tributylammonium bisphosphonate salt is specified
- Process R&D and analytical reference work associated with Cangrelor intermediate supply
- Catalog purchasing for specialty bisphosphonate intermediates
Compare related specialty items such as Novobiocin sodium (CAS 1476-53-5) in the same Custom synthesis range.
Handling & Use Notes
- Assay check: Confirm specification / assay on the batch COA before use (catalog listing: 98%).
- Container handling: Keep sealed and dry; protect from unnecessary moisture and light during sampling.
- Process fit: Verify solubility and stability in your intended organic solvent / reaction system before scale-up.
- Safety: Follow the SDS for storage, PPE and waste handling. Use the batch SDS as the controlling safety document.
Need assay or packing discussion? Email [email protected] or use the contact form.
Packaging, Storage & Logistics
| Standard Pack Sizes | 50 g / 100 g bottles; 500 g / 1 kg packs (custom packing available) |
|---|---|
| Storage | Keep sealed, dry and protected from light and heat. Follow the batch COA and SDS |
| Shelf Life | Confirm shelf life on the COA for each lot |
| MOQ | Commercial MOQ discussed per project (often from 50 g); larger packs available on request |
| Lead Time | Stock items often ship promptly; custom pack / large lots typically 7–14 working days |
Quality & Documentation
For Tributylamine (dichloromethylene)bis(phosphonate) (CAS 163706-61-4), Monuo Chemical can provide:
- Certificate of Analysis (COA)
- Technical Data Sheet (TDS) and Safety Data Sheet (SDS)
- CAS / product-name confirmation for your purchase file
- Flexible packing from grams to kilograms
- FOB / CIF / DAP terms as agreed
Our team aims to return technical data and quotations within 24 hours. See also Custom synthesis.
Request a Quote
Share your target assay, pack size and destination. We will confirm availability and documentation for Tributylamine (dichloromethylene)bis(phosphonate) CAS 163706-61-4.
Request a Quote | Email: [email protected]
Frequently Asked Questions
What is Tributylamine (dichloromethylene)bis(phosphonate) (CAS 163706-61-4)?
It is a tributylammonium salt of dichloromethylene bisphosphonic acid, commonly listed as a Cangrelor intermediate. Monuo Chemical lists it under Custom synthesis. Match CAS 163706-61-4 on the batch COA.
Is this the same as clodronic acid?
Not exactly. This CAS is the 1:1 tributylamine salt form used in catalog Cangrelor intermediate routes, not free clodronic acid alone. Always specify CAS 163706-61-4 on RFQs and POs.
What is the molecular formula and weight?
Listed values are molecular formula C13H31Cl2NO6P2; molecular weight about 430.24 g/mol. Confirm on the batch COA/TDS.
Where is this intermediate typically used?
Typical R&D uses include Cangrelor synthesis and related nucleotide-analog bisphosphonate introduction steps. Monuo supplies raw-material identity documentation only; finished-product claims remain the customer’s responsibility.
What specification do you supply?
A catalog listing for this CAS is 98%. Exact assay is confirmed on the Certificate of Analysis for each lot. Share your target grade when you request a quote.
How should this material be stored?
Keep sealed, dry and protected from unnecessary light and heat. Follow the batch SDS and COA for controlling storage conditions.
How do I request a quotation for CAS 163706-61-4?
Share target assay, pack size and destination via the Request a Quote page or email [email protected]. We aim to reply within 24 hours.
Which related Custom synthesis products can I review?
You may also review Novobiocin sodium (CAS 1476-53-5) and 5-Vinylpyrrolidone (CAS 7529-16-0), or open the full Custom synthesis catalog.
Related Products
- Novobiocin sodium (CAS 1476-53-5)
- 5-Vinylpyrrolidone (5-VP) (CAS 7529-16-0)
- Methyl Oxalyl Chloride (CAS 5781-53-3)
- View all Custom synthesis
Disclaimer: Information is for specialty chemical raw-material identification and technical reference. Finished-product claims and regulatory filings remain the customer’s responsibility. Verify each lot against the supplied COA and SDS. Trade terms are FOB / CIF / DAP as agreed.
