Rapamycin (CAS 53123-88-9) is supplied by Monuo Chemical for specialty chemical and custom synthesis purchasing. It is also referenced as Sirolimus, AY-22989 and NSC-226080. Buyers typically search by product name or CAS when sourcing macrolide biochemicals for mTOR pathway and cell-biology research.
Key Specifications at a Glance
| Product Name | Rapamycin |
|---|---|
| CAS Number | 53123-88-9 |
| Molecular Formula | C51H79NO13 |
| Molecular Weight | 914.17 g/mol |
| Chemical Class | Macrolide / mTOR pathway biochemical |
| Purity / Specification | 98%; confirm assay on the batch COA |
| Typical Use Area | Cell-biology / biochemical R&D; mTOR signaling studies |
| Category | Custom synthesis |
| Documents | COA, TDS, SDS on request |
| Supply Origin | China | Worldwide shipping |
What Is Rapamycin?
Rapamycin (CAS 53123-88-9), also known as Sirolimus, is a macrocyclic lactone originally associated with Streptomyces hygroscopicus. Molecular formula C51H79NO13; molecular weight about 914.17 g/mol. Always match CAS 53123-88-9 on the batch COA.
In laboratory literature it is widely used as a potent, selective probe of the mammalian target of rapamycin (mTOR) pathway: it binds FKBP12 and the resulting complex allosterically inhibits mTORC1. Monuo Chemical supplies Rapamycin as a specialty chemical raw material under Custom synthesis, with batch identity documentation (COA / SDS). Finished-product claims, labeling and local regulatory filings remain the brand manufacturer’s responsibility. Confirm grade and assay against the batch COA for your intended method.
Synonyms & Search Names
- Rapamycin
- Sirolimus
- AY-22989 / AY 22989
- NSC-226080
- RPM / RAPA (research abbreviations)
- CAS 53123-88-9
Applications
In specialty biochemical and cell-biology R&D projects, Rapamycin is commonly reviewed for:
- mTOR / mTORC1 pathway inhibition studies via the FKBP12–rapamycin complex
- Autophagy and related cell-signaling model systems
- Translation initiation / cell-cycle research where a defined mTORC1 probe is required
- Catalog purchasing for custom synthesis of specialty macrolide biochemicals
Compare related specialty items such as Novobiocin sodium (CAS 1476-53-5) in the same Custom synthesis range.
Handling & Use Notes
- Assay check: Confirm specification / assay for Rapamycin on the batch COA before use.
- Container handling: Keep sealed and dry; protect from unnecessary light and heat during sampling.
- Process fit: Verify solubility and stability in your intended solvent / media system before scale-up.
- Safety: Follow the SDS for storage, PPE and waste handling. Use the batch SDS as the controlling safety document.
Need assay or packing discussion? Email [email protected] or use the contact form.
Packaging, Storage & Logistics
| Standard Pack Sizes | 50 g / 100 g bottles; 500 g / 1 kg packs (custom packing available) |
|---|---|
| Storage | Keep sealed, dry and protected from light and heat. Follow the batch COA and SDS |
| Shelf Life | Confirm shelf life on the COA for each lot |
| MOQ | Commercial MOQ discussed per project (often from 50 g); larger packs available on request |
| Lead Time | Stock items often ship promptly; custom pack / large lots typically 7–14 working days |
Quality & Documentation
For Rapamycin (CAS 53123-88-9), Monuo Chemical can provide:
- Certificate of Analysis (COA)
- Technical Data Sheet (TDS) and Safety Data Sheet (SDS)
- CAS / product-name confirmation for your purchase file
- Flexible packing from grams to kilograms
- FOB / CIF / DAP terms as agreed
Our team aims to return technical data and quotations within 24 hours. See also Custom synthesis.
Request a Quote
Share your target assay, pack size and destination. We will confirm availability and documentation for Rapamycin CAS 53123-88-9.
Request a Quote | Email: [email protected]
Frequently Asked Questions
What is Rapamycin (CAS 53123-88-9)?
It is a macrolide biochemical (also called Sirolimus) commonly used as an mTORC1 pathway probe via FKBP12 binding. Monuo Chemical lists it under Custom synthesis. Match CAS 53123-88-9 on the batch COA.
Is Sirolimus the same material?
Yes. Sirolimus is the common pharmaceutical / catalog synonym for Rapamycin. Always specify Rapamycin (or Sirolimus) and CAS 53123-88-9 on RFQs and POs.
What is the molecular formula and weight?
Listed values are molecular formula C51H79NO13; molecular weight about 914.17 g/mol. Confirm on the batch COA/TDS.
Where is Rapamycin typically used in R&D?
Typical laboratory uses include mTOR / mTORC1 inhibition studies, autophagy model systems, and related cell-signaling research. Monuo supplies raw-material identity documentation only; finished-product claims remain the customer’s responsibility.
What specification do you supply?
A catalog listing for this CAS is 98%. Exact assay is confirmed on the Certificate of Analysis for each lot. Share your target grade when you request a quote.
How should Rapamycin be stored?
Keep sealed, dry and protected from unnecessary light and heat. Follow the batch SDS and COA for controlling storage conditions.
How do I request a quotation for CAS 53123-88-9?
Share target assay, pack size and destination via the Request a Quote page or email [email protected]. We aim to reply within 24 hours.
Which related Custom synthesis products can I review?
You may also review Novobiocin sodium (CAS 1476-53-5) and Bis(4-methacryloylthiophenyl) Sulfide (CAS 129283-82-5), or open the full Custom synthesis catalog.
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Disclaimer: Information is for specialty chemical raw-material identification and technical reference. Finished-product claims and regulatory filings remain the customer’s responsibility. Verify each lot against the supplied COA and SDS. Trade terms are FOB / CIF / DAP as agreed.
